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Axion ISTAND Announcement
News
Maestro MEA Platform Powers First Stem Cell Cardiac Safety Assay in FDA ISTAND Program
Author: Axion BioSystems
Product: Maestro MEA, Cardiac Module, CytoView MEA Plate,
Biomimetics, 16 February 2026
Publication
Bio-Compatibility Analysis of Newly Developed Plug and Cuff Electrodes for Future Neuronal Interface Applications
Author: E. Zingkou, G. Pampalakis, A. Kolianou, N. Rossopoulou, A. Skiada, L. Galouni, P. Śniarowski, L. Madej-Kiełbik, G. Sotiropoulou, K. Gzyra-Jagieła, T. Katsila, C. Moldova, M. Ion, O. N. Ionescu, E. Franti, D. Dragomir, G. Siekmeyer, and P. Grotemeyer
Product: Exact FL,
Molecules, 13 February 2026
Publication
Study of the Cytotoxic and Wound Healing Activity of Polysaccharides from Bovistella utriformis
Author: A. Maaloul, P. Valverde-Guillén, C. Cárdenas-García, C. P. Manríquez, M. Araya-Rojas, M. Marí-Beffa, V. Fajardo, and R. T. Abdala Díaz
Product: Lux,
einstein, 13 February 2026
Publication
Guided and unguided neural organoids play complementary roles in studying neurodevelopment and neuroinflammation
Author: R. Josino, B. Y. Yokota-Moreno, I. de Sousa Nóbrega, A. L. Teles e Silva, M. B. Bachir Moysés, G. G. Ferreira, M. S. Branquinho, E. V. Branco, M. R. Passos-Bueno, and A. L. Sertié
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Scientific Reports, 10 February 2026
Publication
Protective effect of Baicalin against doxorubicin-induced cytotoxic and electrophysiological damage in human iPSC-cardiomyocytes
Author: A. Ulivieri, L. Lavra, F. Magi, A. Morgante, E. Martinelli, and L. B. Salehi
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
Advanced Science, 10 February 2026
Publication
β-Adrenergic Signaling Promotes Anti-Tumor Immunity in TP53-mutant Oral Squamous Cell Carcinoma
Author: F. O. Gleber-Netto, D. Silverman, T. Xie, S. Akhter, N. R. Vaughn, A. Adebayo, K. C. Debnath, S. Naara, S. Islam, E. Knutsen, E. L. Ashkin, S. Anfossi, S. Leahey, P. Hwu, S. Talbot, E. K. Sloan, R. Saddawi-Konefka, R. Rangel, J. N. Myers, G. A. Calin, and M. Amit
Product: Maestro Edge, MEA Viability Module, CytoView MEA Plate,
Frontiers in Cellular and Infection Microbiology, 10 February 2026
Publication
Evaluation of neurotoxicity of drugs from morphological and electrophysiological endpoints using human iPSC-derived neural cell models
Author: Z. Qu, S. Li, J. Qiu, G. Huo, Y. Liu, D. Zhang, Y. Yang, X. Geng, and Z. Lin
Product: Maestro MEA, Maestro Pro, Neural Module, CytoView MEA Plate,
Stem Cell Reports, 10 February 2026
Publication
Human neuronal networks on micro-electrode arrays as a tool to assess genotype-phenotype correlation in CACNA1A-related disorders
Author: M. P. Hommersom, S. Puvogel, N. Scheefhals, E. Carpentiero, M. Bouma, E. van Beusekom, L. Dillen, B. P.C. van de Warrenburg, N. N. Kasri, and H. van Bokhoven
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Advanced Healthcare Materials, 03 February 2026
Publication
A Tri-Culture Heart-on-a-Chip Platform With iPSC-Derived Cardiac Cells for Predictive Cardiotoxicity Testing
Author: K. Tadevosyan, J. Yeste, M. Alvarez, D. Marrero, L. Casado-Medina, Y. Richaud-Patin, O. García-Iglesias, J. Litowczenko, A. M. Garcia, A. Guimerà, X. Illa, R. Villa, and A. Raya
Product: Lux,
Advanced Healthcare Materials, 01 February 2026
Publication
Controllable Dynamic Mechanical Cell Stimulation using Magnetically Actuated Artificial Cilia
Author: R. Kooi, T. Ul Islam, O. M.J.A. Stassen, N. Amsing, J. de Boer, and J. M.J. den Toonder
Product: Lux,
Molecular Psychiatry, 31 January 2026
Publication
SHANK3 deficiency alters early progenitor dynamics and reveals shared pathways with neurodegeneration
Author: E. Varella-Branco, E. Shephard, V. H. C. Toledo, I. C. Ramos, E. C. M. Lacerda, L. L. M. Carvalho, M. A. Fiuza, M. Paschalidis, C. I. S. Costa, A. C. S. Girardi, A. C. V. Krepischi, E. B. Casella, G. Polanczyk, K. Griesi-Oliveira, F. Papes, L. Alvizi, G. S. Kobayashi, and M. R. dos Santos e Passos Bueno
Product: Maestro MEA, Neural Module, CytoView MEA Plate,
Journal of Oral Biosciences, 29 January 2026
Publication
Modeling GABAergic hyperexcitability in sleep bruxism patient-derived brainstem neurons using a multielectrode array platform
Author: M. Onishi, A. Yamaguchi, Y. Abe, T. Sato, M. Fujishima, W. Akamatsu, and K. Baba
Product: Maestro MEA, Neural Module, CytoView MEA Plate,
Advanced Science, 27 January 2026
Publication
Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC-Derived Cortical Organoids
Author: S. R. Labra, J. Compher, A. Prabhavalkar, M. Almaraz, C. C. Kwong, C. Baal, M. Talantova, N. Dolatabadi, J. Piña-Sanz, Y. Wang, L. Yoon, S. Ghatak, Z. Gao, Y. Zhang, D. Trudler, L. Massey, W. Lin, A. Balistreri, M. Bula, N. J. Schork, T. S. Mondala, S. R. Head, J. W. Kelly, and S. A. Lipton
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Biochemical Society Transactions, 27 January 2026
Publication
Human iPSCs: atrial versus ventricular cardiomyocytes and their functional and pharmacological differences
Author: S. D. Broadbent, J. R. Bhagwan, T. Olusoga, and A. Barnes
Product: Maestro MEA, Cardiac Module, CytoView MEA Plate,
Cell Reports, 27 January 2026
Publication
Mucosal innate immune activation as the trigger to Prevotella species-induced arthritis in genetically resistant mice
Author: Y. Maeda, M. Rabenow, E. Schmid, N. Otterbein, I. Gimaev, L. Amend, L. Riedinger, L. Ehnes, I. Miyagawa, I. Sarfati, T. R. Lesker, H. Danzer, K. Sarter, K. Dürholz, F. Schälter, L. Bao, S. Wirtz, P. Arnold, J. Hofmann, M. Pischetsrieder, D. Sjöberg, A. Svärd, A. Kastbom, G. Schett, T. Strowig, and M. M. Zaiss
Product: Maestro Z, Impedance Module, Maestro Z,
Neurobiology of Disease, 24 January 2026
Publication
Pharmacological manipulation of nested oscillations in human iPSC-derived 2D neuronal networks
Author: D. Pré, C. Cazares, A. T. Wooten, H. Zhou, I. Onofre, A. Neil, T. Logan, R. Hu, J. H. Lui, B. Voytek, and A. G. Bang
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Journal of Medicinal Chemistry, 23 January 2026
Publication
Development of Novel Small-Molecule Targeting SCN1A-Associated Severe Myoclonic Epilepsy of Infancy
Author: D. G. Kim, K. S. Hwang, S. H. Ahn, S. S. Kim, Y. Son, S. B. Park, W. H. Jung, D. S. Shin, S. H. Cho, B. W. Choi, P. Kim, Y. Heo, M. Kim, J. Y. Yang, K. R. Lee, H. A. Lee, J. Kim, H. C. Kang, K. Y. Kim, M. A. Bae, and J. H. Ahn
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Nature Communications, 22 January 2026
Publication
Synaptic and intrinsic membrane defects disrupt early neural network dynamics in Down syndrome
Author: S. B. Hannan, I. Alić, A. Murray, J. Kwon, M. Mortensen, H. J. Kang, A. Plećaš, P. A. Goh, N. L. O’Brien, R. Naud, D. Nižetić, and T. G. Smart
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Radiation, 21 January 2026
Publication
In Vitro Perspective on Hypofractionated Radiotherapy in Breast Cancer
Author: P. du Plessis, P. Busisiwe Nkosi, S. Nair, and J. Akudugu
Product: Lux,
Frontiers in Bioengineering and Biotechnology, 20 January 2026
Publication
A cross-correction gene therapy approach for CDKL5 deficiency disorder improves the pathological phenotype of CDD patient-derived cortical organoids
Author: G. Medici, A. M. Bove, S. Trazzi, F. Puppo, M. Loi, N. Mottolese, G. Candini, F. Trebbi, S. Sanchez, A. R. Muotri, and E. Ciani
Product: Maestro MEA, Neural Module, CytoView MEA Plate,